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Research on a ternary compound formula containing ginsenoside Rg1, tetrandrine, and icaritin (GTI) can mitigate atopic dermatitis-like symptoms by reducing the infiltration of eosinophils, mast cells, and CD4 + T cells in skin tissue, as well as reducing IgE-mediated reactions and inhibiting MAPK signaling activation

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Trial registration www.anzctr.org.au ACTRN12621000878875 Funding The study was not funded by a specific research grant

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further demonstrated that GLP-1RAs suppress alcohol-induced locomotor stimulation and DA release in the NAc, suggesting that GLP-1R signaling can dampen mesolimbic sensitization to ethanol [24]