Nobody has been able to establish a lethal dose (LD50), even at concentrations way beyond what's used in typical protocols
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The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: a review of literature
These effects were generally mild and transient
If you suspect sensitivity to a particular B12 preparation, discuss switching formulations with your GP or pharmacist
Selank demonstrates anxiolytic and potentially analgesic properties that may help with pain perception modulation