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In contrast, iTregs arise in the periphery, where cytokines such as TGF- and IL-2 promote their antigen-induced Foxp3 expression and suppressive function, thereby establishing tolerance to foreign antigens

It is part of a complex antioxidant system that works synergistically to retain redox balance

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Stable gastric pentadecapeptide BPC 157 therapy for monocrotaline-induced pulmonary hypertension in rats leads to prevention and reversal

doi: 10.1155/2018/4067597, 11

This would seem to be a potentially fruitful area for further research since the major environmental risk factors for PDexposure to pesticides, trichloroethylene, and air pollutionare likely to have their effects on dopaminergic neurodegeneration via toxic effects of oxidative stress and inflammation 61