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10.1002/hep.30670 22 CusiK.SattarN.Garcia-PerezL

In this section, we will review the most used and promising tools for BBBP assessment and HT prediction, each of which has its own advantages and disadvantages (Table 1)

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Additionally, Ozempic and Wegovy specifically have been linked to GLP-1 vision loss side effects due to a rare condition known as non-arteritic anterior ischemic optic neuropathy (NAION)

At the population level, GLP-1RAs have been shown to enrich SCFA-producing genera including Roseburia and Ruminococcus and promote Akkermansia muciniphila colonization (a bacterium whose bioactive protein P9 independently stimulates further GLP-1 secretion) while simultaneously suppressing pathobionts including Escherichia coli and Enterococcus by reducing endotoxemia and restoring barrier function

These methodological limitations underscore the need for future research using longitudinal designs and more robust data collection methods to validate and expand upon the findings