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For bioinformatics analysis, data normalization was conducted using the Trimmed Mean of M -values method in edgeR, and pathway analyses were performed with Fishers exact test
& Navas, P
J Hepatol (2010) 53:93440
ScienceDirect Glutathione decline after menopause
The main enzymes involved in enzymatic reactions are uncoupled endothelial nitric oxide synthase (eNOS), NADPH oxidase (NOX), xanthine oxidase (XO), arachidonic acid (ARA), peroxidase, and metabolic enzymes such the cytochrome P450 system, cyclooxygenase, and lipoxygenase
Among these proteins, SERPINA3 also negatively correlated with the ALSFRS-R score ( P = 0.0444) at the first visit
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