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This temporal regulation optimizes healing outcomes while minimizing scar tissue formation, as demonstrated in multiple animal wound models and human clinical trials

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For instance, a randomized controlled trial comparing dexmedetomidine and lorazepam in adult mechanically ventilated ICU patients found that dexmedetomidine allowed patients to have more delirium-free time (190)

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Neurotrauma 29 , 678705 (2012)