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Block randomization and allocation concealment was done using sequentially numbered, opaque sealed envelopes (SNOSE) and monitored by the central coordinator

Tirzepatide-based medications include Mounjaro (diabetes) and Zepbound (weight loss)

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These data can be found at Conflicts of Interest The authors declare no conflicts of interest

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Antioxidant mechanisms include enhanced expression of molecules that can modulate ROS accumulation by both enzymatic and nonenzymatic meansGlutathione (GSH) is an antioxidant that acts as a free radical scavenger and a detoxifying agent in cells