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However, plant GPXs are classified in the pyridoxine protein group due to an efficiently reduction of peroxide via the thioredoxin regenerating system ( Supplementary Table S2 ) ( Moreover, GPX3 plays a pivotal role in ABA-mediated stress signaling by interacting with phosphatases ABI1 and ABI2, key regulators of this pathway ( Figure 5 )

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While clinicians should not limit their usage due to cancer concerns, they must maintain a thorough surveillance for possible adverse outcomes