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Safety, tolerability, pharmacokinetics, and pharmacodynamics of the first-in-class GLP-1 and amylin receptor agonist, amycretin: a first-in-human, phase 1, double-blind, randomised, placebo-controlled trial

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2020;3:e00131

Compound K attenuates hyperglycemia by enhancing glucagon-like peptide-1 secretion through activating TGR5 via the remodeling of gut microbiota and bile acid metabolism

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A Maintenance Plan Matters Nutrition, physical activity, follow-up care, behavioral support, and sometimes continued medication or a procedure may be needed to maintain progress