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Notably, oral semaglutide [15] underwent evaluation at doses as high as 50 mgan increase of over threefold compared to the presently available 14 mg dosefor the management of type 2 diabetes

PubMed Lincoff AM, Brown-Frandsen K, Colhoun HM, et al

PMID: 39498283

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This is why we recommend that patients lose no more than 1-2 pounds per week, get at least 20% of their calories from protein, and add weight bearing exercises to their workout routine 2-3 times per week