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Journal reference: Ceasovschih A, Asaftei A, Lupo MG, et al

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Phase 1 involves enrolling 100 patients to a refined ePRO intervention, assessing initial outcomes, and gathering qualitative feedback from patients and providers through semi-structured interviews

In terms of microbiome-targeted therapy, the review notes that although migraine patients often exhibit altered gut microbiota, current meta-analyses do not support a consistent benefit from probiotic supplementation, indicating a need for more refined, individualized approaches

But when plant cells go to the gut, the bacteria there release enzymes to break down their cell walls. Their approach also avoids a step in the production of conventional GLP-1 receptor agoniststhe post-translational modifications, or chemical changes made to peptides after synthesis, required to make them functional

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