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And the answer is not as simple as either side wants it to be

Under normal physiological conditions, the fed state leads to increased circulating glucose, which stimulates the secretion of insulin from pancreatic -cells

McDonnell, T., Cussen, L., McIlroy, M

Given the tendency of these drugs to quiet food noise, and reduce cravings, the treatment of addiction is another area where scientists see a lot of potential for GLP-1s