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The lowest-energy docking pose for each ligand was selected for visualization and analysis in PyMOL (v3.1.6.1), with particular attention to measuring the distance between the ligands disulfide ring and the selenium atom of Sec498 to validate the binding geometry

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FIGURE 7 Hybrid metallodrugs based on ruthenium and curcumin have attracted attention as potential anticancer agents, owing to the favourable pharmacological profile of ruthenium complexes combined with curcumins bioactivity

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