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Effects on aging-related biology, cognitive performance, energy metabolism, antioxidant defense, or tissue repair (depending on the compound) are mediated through specific receptor or enzymatic pathways

Protective effect of resveratrol on oxidative damage in male and female stroke-prone spontaneously hypertensive rats

Similarly, NEK7 is glutathionylated at Cys253 and requires GSTO1-dependent deSSG to interact efficiently with NLRP3 67

Alpha-lipoic acid works like a master recycler, helping regenerate glutathione after it's been used up neutralizing free radicals

When levels are low, cells are left more vulnerable to oxidative damage accelerating the aging process and increasing the risk of various chronic diseases

doi: 10.1111/rda.2018.53.issue-4 187 IsbilenEKulaksizogluSKirmiziogluMKaruserci KomurcuOTaburS