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[DOI] [PMC free article] [PubMed] [Google Scholar] 195.Su Q., Wong O.W.H., Lu W., Wan Y., Zhang L., Xu W., Li M.K.T., Liu C., Cheung C.P., Ching J.Y.L., et al

Weight regain can happen if GLP-1 therapy is stopped abruptly without lifestyle support

This is doubly important on GLP-1 medications, which suppress appetite and make it easy to under-eat protein and lose muscle along with fat

For instance, one study found that 6 h of voluntary running significantly increased full-length BDNF mRNA in rats, with further elevation after 12 h

As a result, the tirzepatide group had a reduced need for eye treatments such as intraocular injections or laser therapy