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Taken together, these findings demonstrate that oral butyrate suppresses the mTORC1ISR axis both peripherally and centrally, thereby attenuating PBAT-MPs-induced microglial lipotoxicity, neuroinflammation, and cognitive decline via the gutbrain axis

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Our structures also provide clues for understanding the mechanism of the basal activity of the ghrelin receptor

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GLOW is also different from Wolverine and KLOW