[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Zhang Y., Wang X.L., Zhou M., Kang C., Lang H.D., Chen M.T., Hui S.C., Wang B., Mi M.T
This innovative approach to shedding excess weight has been gaining traction, promising results where traditional methods have fallen short
This includes the first oral GLP-1s approved for weight loss (Wegovy pill, Foundayo) and GLP-1 injections (Wegovy, Zepbound, Ozempic)
In the pancreas, activation stimulates glucose-dependent insulin secretion, meaning insulin is released only when blood glucose levels are elevated, which reduces the risk of hypoglycemia compared to some other diabetes medications
Mounjaro has demonstrated a favourable safety profile with generally mild to moderate gastrointestinal side effects, similar to established GLP-1 receptor agonists
These effects likely stem from GLP-1s action on brain receptors involved in reward processing