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Besides its profound body weight-reducing effect, tirzepatide also showed a significant ability to reduce liver fat content (measured by magnetic resonance imaging-proton density fat fraction) compared with insulin degludec in the subpopulation of patients with T2DM in the SURPASS-3 study.29 These data provide additional evidence on the metabolic effects of this novel GLP-1/GIP dual RA

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Peak Reduction Heights reduction is once weight loss ceases to increase and plateaus

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Self-amplifying loop of nf-b and periostin initiated by Piezo1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration