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placebo resulted in significant decreases in total cholesterol, LDL-C, VLDL-C, free fatty acids, and triglycerides and an increase in HDL-C at week 68 of follow up [33]

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Many neuroprotective effects remain to be causally associated with anti-inflammatory mechanisms, and some Alzheimers disease mouse models did not respond to semaglutide or tirzepatide, emphasizing that not all neural benefits are consistent across studies

Note: these are averages, suggesting that some patients did not lose as much weight, whilst others exceeded these numbers

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