doi: 10.1056/NEJMoa2413258, PMID: [DOI] [PubMed] [Google Scholar] 4
GLP-1s are a class of medications, like semaglutide, that mimic a natural hormone in your body
The fact that tirzepatide at therapeutic doses did not push calcitonin into concerning ranges provides direct biochemical evidence against the rodent-to-human translation of C-cell risk
343 The additional unexpected observations from the GLP-1, GIP and GCGR tri-agonist studies 342,344 warrant further investigation, as these studies highlight the incomplete understanding of metabolic hormonal synergism, and that further elucidation of this will likely lead to more efficacious treatments for diseases such as T2D
It is also claimed to boost the wound healing process and is especially helpful for sensitive skin types (acne, rosacea, inflammation-related skin diseases)
Negi G, Kumar A, Joshi RP, Sharma SS