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Nuclear receptor coactivator 4 (NCOA4) enhances free iron levels by binding to ferritin-heavy chains and aiding its transport through the lysosome
That means it activates two different incretin hormone receptors simultaneously
10.1001/jamacardio.2017.4069 19 BiJ.ZhangJ.RenY.DuZ.LiQ.WangY.et al (2019)
PLoS ONE 6 , e24109 (2011)
By rebuilding the FOXO1 activity, there was impaired proliferation and apoptosis
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