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Evidence in one sentence: Both delivery systems are biologically plausible and supported by limited human biomarker or pharmacokinetic data, but neither has been proven superior for meaningful clinical outcomes

Am J Physiol Cell Physiol 290:C616C625 Drevets WC, Thase ME, Moses-Kolko EL et al (2007) Serotonin-1A receptor imaging in recurrent depression: replication and literature review

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[1] [11] While there is no evidence that Ozempic worsens heart failure, the limited data in patients with advanced cardiac dysfunction means treatment decisions should involve cardiology input and individualised risk-benefit assessment

Many patients find it helpful to select a time that fits naturally into their weekly routine, making it easier to remember and maintain adherence