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The exact cause is unclear, but the textbooks describe several recognised contributors: Focal increase in melanin within the basal layer (the deepest, foundation layer of the mouth lining) of the lining, with or without an increase in the number of melanocytes (the cells that make melanin)

Cela signifie que les cellules peuvent mtaboliser les nutriments plus efficacement, convertissant les glucides, les lipides et les protines en nergie utilisable

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But the binding of Quercetin induces a negative correlation (Fig

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