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10.1016/j.ebiom.2020.102974 39 ConeR

Lung Cancer 84 , 121126 (2014)

Diabetes Ther 12, 13251339 (2021)

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A high B12 that does not fit the patient is a reason to ask whether the result reflects an assay artifact

Additionally, a randomized, double-blind, placebo-controlled trial in 2,588 healthy older adults with mild hyperhomocysteinemia found that daily supplementation with 500 g of vitamin B 12 and 400 g of folic acid for two years reduced blood homocysteine concentrations but had no benefit on depressive symptoms in those with or without depressive symptoms at baseline (110)