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In addition, a study comparing the effects of acupuncture and metformin in obese/overweight women and thin women with IR and PCOS found that acupuncture and metformin showed similar effects in thin women with IR and PCOS, but in those of obese/overweight women, acupuncture was less effective in increasing insulin sensitivity compared to metformin [144]

Age-matched db/+ mice served as a control group (Healthy control)

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