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GLP-1 has a variety of physiological functions, which can regulate blood glucose level by promoting insulin secretion and synthesis, stimulating -cell proliferation and inducing islet regeneration, inhibiting -cell apoptosis and glucagon release, delaying gastric emptying and controlling appetite (Mller et al., 2019

Compliance with GLP principles was verified during the inspection

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For the first 14 weeks of the study, participants received cagrilintide and semaglutide as 2 separate injections in the stomach area

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