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Glutamate is the primary excitatory neurotransmitter in the central nervous system and opens non-selective cation channels
Chen WW, Zhang X, Huang WJ
GLP-1 drugs are generally contraindicated Personal or family history of medullary thyroid cancer (MTC): GLP-1 drugs carry a boxed warning for thyroid C-cell tumors in rodent studies Multiple Endocrine Neoplasia syndrome type 2 (MEN 2): Increased MTC risk History of pancreatitis: GLP-1 drugs may increase pancreatitis risk Type 1 diabetes: Not studied
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