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This directly sensitizes osteoclasts to osteoclastogenic signals and entrains ROS-enhanced expression of cytokines that promote osteoclastic bone resorption

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According to the new guidelines, doctors, in general, should offer access to appropriate drugs to adolescents 12 and older who are faced with obesity and offer referrals for weight-loss surgery to those 13 and older with severe obesity

Comprehensive medical evaluation and aggressive nutritional support are particularly important in this age group

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