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Agarwal, A., et al
The short half-life of glucagon-like peptide-1 in plasma does not reflect its long-lasting beneficial effects
JAMA (2022) 327:53445
Lillys Zepbound, approved in November 2023 as the Indiana-based drug giants answer to Novo Nordisks Wegovy, showed 21% average weight loss after 72 weeks for its highest dose in its Phase 3 trial, and a mid-stage study of another Lilly experimental medicine, called retatrutide, showed 24% weight loss after just 48 weeks
Once mixed correctly, the solution can be measured accurately using a suitable syringe