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Enhancement of purine nucleotide synthesis via the pentose phosphate pathway was found to be advantageous for cell proliferation and tumorigenesis of NRF2-addicted cancer cells (Mitsuishi et al

Seek emergency care right away if these symptoms appear

NAC, the non-toxic cysteine)

Continued development of new pH-sensitive cleavable linkers with tunable release rates is essential for advancing prodrug and gene-delivery systems

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Folinic acid, unlike standard folic acid, can bypass the blocked folate receptor through an alternative transport pathway and restore folate delivery to the brain