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Specifically, upregulation of DNA repair proteins, such as excision repair cross-complementation group 1 and BRCA 1/2, can enhance the repair of cisplatin-induced DNA damage, thereby reducing the cytotoxic effects of the drug (58)

PMID: 30477533

In another study, researchers discovered that tirzepatide treatment, when combined with a decrease in circulating levels of branched-chain amino (BCAA) and keto (BCKA) acid metabolites linked to the development of systemic insulin resistance (IR) and T2DM improves insulin sensitivity in obese mice and humans with T2DM [82]

Medications and topical treatments Your dermatologist may prescribe medications or topical treatments to help lighten melasma

Stockholm, Sweden: Institute for Futures Studies (2007)