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Overall, the V229A receptor presented with biased signalling favouring G s coupling over -arrestin 2 recruitment and receptor localisation and activation at the plasma membrane

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Additionally, partner Chris Seeger is lead counsel in the Depo-Provera Products Liability Litigation, which claims Pfizer misrepresented the long-term safety of the injectable birth control Depo-Provera and failed to warn of the increased risk of intracranial meningiomas, a type of brain tumor