does semaglutide make you gain weight GLP-1 Cause Gain? What Research Shows Weight Change With Semaglutide

After one year: Continued max dose: weight loss essentially fully maintained Stepped down to 5 mg: weight loss largely maintained, with an average regain of about 12 pounds Switched to placebo: large regain, with roughly 67% of patients eventually requiring rescue therapy That 12-pound tradeoff is the answer to the question patients ask most often: What does it actually cost me to step down

The doctor will review your full medical history, including any existing conditions such as thyroid issues, pancreatitis, or severe gastrointestinal disease, and current medications, to ensure your safety and the medication's effectiveness

Your healthcare provider can also diagnose B12 deficiency based on your medical history and physical exam

The hunger effect is dramatically reduced or absent

Karimi 2005

It stays stable in water and in gastric juice