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However, long-term outcomes of side effects are still being established

Researchers are also studying retatrutide in metabolic-associated fatty liver disease, reflecting how broadly its mechanisms reach across metabolic health

Hepatic Fat and MASH Research: Glucagon receptor activation promotes lipolysis and fatty acid oxidation in the liver, reducing hepatic fat content

Maynard, C

M.NoureddinM.AlkhouriN.et al (2024)

The theory is that supporting the body natural GLP-1 production while also using a pharmaceutical agonist could provide complementary benefits, particularly for gut health and microbiome diversity