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Finch Alfred Alembick Mrs

JAMA 2011;305:1659-1668

Acetaldehyde Toxicity When your liver breaks down ethanol, it produces a byproduct called acetaldehyde, which is significantly more toxic than alcohol itself and is a primary driver of hangover symptoms (Mackus et al., 2020)

other studies have found no significant difference

On a hormonal level, alcohol impacts cortisol (your stress hormone), reduces serotonin levels (which affect mood) and interferes with vasopressin, a hormone that regulates hydration

Tesofensine acts by affecting three brain chemicals: noradrenaline, serotonin, and dopamine, which play a role in controlling hunger