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Hamon and Blier, 2013)

The Triple-Agonist Breakthrough Retatrutide (LY3437943), developed by Eli Lilly, is an investigational triple-agonist peptide that activates three metabolic receptors simultaneously: GLP-1, GIP, and the glucagon receptor

When Pinto has a patient who asks about weaning off their GLP-1 or spacing out dosing, he is very receptive to the conversation

And ask them questions like, is my weight affecting my health

Gradual dose escalation and eating smaller, less fatty meals help minimize this side effect

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