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A comparison of crystallographic and DFT optimized geometries on two taxane diterpenoids and docking studies with phospholipase A2

doi: 10.1016/S2213-8587(14)70225-6 240

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In an animal study, using a mouse model with different age groups, non-alcoholic steatohepatitis (NASH) was induced, revealing age-dependent effects on cardiac function

These modifications result in a longer half-life, allowing for once-weekly dosing rather than daily administration

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