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Nicotine acts on acetylcholine receptors in the brain and increases release of feel good neurotransmitters like serotonin, dopamine and norepinephrine

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Both GLP-1RAs and DPP-4is are guideline-recommended therapeutic options, supporting the ethical appropriateness of the study design (23)

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In response to food ingestion, L cells secrete hormones [77], such as glucagon-like peptide-1 (GLP-1) and peptide YY (PYY)