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Deep brain stimulation of subthalamic neurons increases striatal dopamine metabolism and induces contralateral circling in freely moving 6-hydroxydopamine-lesioned rats

North America has the highest number of type 2 diabetes and obesity cases and has a highly developed healthcare system with greater penetration towards innovative therapies propelling GLP-1 analogues growth

As GLP-1R agonist therapies continue to expand in clinical use, further investigation is warranted to determine the oncogenic implications of this overexpression for thyroid cancer

Cadden IS, Partovi N, Yoshida EM (2007)

Approaches to improvements in efficacy primarily target additional gut hormones via dual- and tri-agonists, and if Mounjaro provides any indication, dual- and tri-agonists may not be likely to enhance tolerability

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