nejm glp 1 publishes Phase 3 trial results for orforglipron, an oral GLP-1 obesity medication. | Scott Isaacs, MD, FACP, FACE posted on the topic Semaglutide in Early Type 1

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The researchers compared the one-year risk of heart failure hospitalization or death in new users of each GLP-1 drug to the risk of those outcomes in a placebo group of patients taking sitagliptin, a diabetes drug known to have no impact on HFpEF

Reauthorization is valid for 12 months

They lack the preservatives found in multidose vials, so saving leftover liquid means injecting a solution defenseless against bacterial contamination

This solution is intended only as a diluent or solvent for the preparation of medications for intravenous, intramuscular, or subcutaneous injection , according to the specific instructions provided by the drug manufacturer

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