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Some pointed to evidence suggesting that not everyone diagnosed with obesity needs to lose weight to stay healthy and bemoaned the use of BMI, a controversial measure that is increasingly considered inadequate unless additional factors such as waist circumference are also evaluated

Dysesthesia, an abnormal sensation often described as tingling, burning, or numbness in the skin, appeared in 8.8% of participants on the 9 mg dose and 20.9% on the 12 mg dose, compared to just 0.7% on placebo

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