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10.1016/j.neuron.2016.12.017 6 BendavitG.AboulkassimT.HilmiK.ShahS.BatistG

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Statins act as competitive inhibitors of HMG-CoA reductase, the enzyme that limits the rate of cholesterol production in hepatocytes, thereby decreasing cholesterol synthesis

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Rapamycin and the recently developed more specific mTOR inhibitors, i.e., rapalogs, are promising therapeutic compounds in the treatment of cancers and several autoimmune and chronic inflammatory diseases [66]

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