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for example one or more carboxylic acid groups (-COOH) may be deprotonated into the carboxylate group (-COO-) and/or one or more amino groups (-NH2) may be protonated into the -NH3+ group

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This slowing of stomach motility can progress from a therapeutic effect to a pathological condition, potentially triggering a cascade of gastrointestinal complications

They make sense conceptually but need clinical trials to determine safety, dosage, timing and interactions

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