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For patients on exogenous glucocorticoid therapy, there is profound suppression of POMC production and hence, MSH production

Half of the volunteers were taking one of three GLP-1 medicationssemaglutide, tirzepatide, or liraglutidewhile the other half werent on any of these drugs

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(2021) injected PTB-ASOs targeted specifically to astrocytes into the cerebrospinal fluid of mice to inhibit PTBP1 expression, and the immunofluorescence results showed a significant increase in tdTomato- and NeuN-labelled neurons in the hippocampus and cortex of mice

Rare risks are minimized with proper screening and technique