Glucose-dependent insulin secretion & metabolic improvements: GLP-1 improves post-meal insulin secretion and lowers glucagon, which improves glycemia and can reduce metabolic drivers of weight gain
Cost is consideration ($1,200-1,400/month projected)
Unlike semaglutide, which targets only the GLP-1 receptor, tirzepatide is a dual-action medication that activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
Coryell Health doesnt recommend taking GLP-1 medications if you: Are pregnant or breastfeeding Have a personal or family history of medullary thyroid cancer (MTC) Have a diagnosis of multiple endocrine neoplasia syndrome type 2 Have a history of pancreatitis Have severe gastrointestinal conditions Side effects of taking a GLP-1 medication may include: Loss of appetite Nausea and vomiting Diarrhea Dizziness Mildly increased heart rate Pancreatitis Medullary thyroid cancer (MTC) Acute kidney injury If youre unsure whether an existing condition, your personal history or your family history will not mix well with a GLP-1 medication, talk with your Coryell Health primary care provider to determine whether a GLP-1 medication is right for you
After just a few days with BuildLeaf, my appetite decreased and I felt more balanced. Week 3: Three weeks in, the fat around my stomach started shrinking
BMC Endocr