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2010 in J Clin Endocrinol Metab pooled the original Phase 3 with the confirmatory NCT00435136 (combined n = 816) and reported sustained visceral-adipose-tissue reduction over 52 weeks alongside broadly stable glucose parameters [7]

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Studies show that patients who continue with the semaglutide 2.4mg injection are able to keep off most of the weight they lose, while those who discontinue may experience gradual regain

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Think of the IRR as a "Master Switch" for healing that exists on the surface of cells, particularly immune cells and nerve cells

doi: 10.1038/nprot.2007.152