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Increased oxidative damage has been detected in both sporadic and familial ALS patients carrying SOD1 mutations (Tortelli et al., 2020)

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When injected into the tail vein of mice with MDA-MB-435 breast cancer xenografts, LyP-1 peptide by itself inhibited tumor growth and reduced the number of lymphatic vessels, thus demonstrating a cytotoxic activity of the peptide

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