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And the paper on Nature Medicine in 2003 describes how the GLP-1 receptor in the hippocampus is involved in cognition

200,201,202 Simultaneously, Akt promotes cell survival by phosphorylating and inhibiting a series of pro-apoptotic proteins, such as Bad and the FOXO family

Endocrinology (2014) 155(4):128090

De Giorgi R, Ghenciulescu A, Yotter C, Taquet M, Koychev I (2025) Glucagon-like peptide-1 receptor agonists for major neurocognitive disorders

doi: 10.1152/ajpendo.00250.2023

In July 2023, the EMA initiated an inquiry into safety concerns after receiving approximately 150 spontaneous reports indicating potential links between drugs and suicide ideation or self-harm [72]