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This decrease is important as cocaine has been shown to increase 2-AG tone in the brain

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Preclinical data suggest GIP receptor engagement modulates lipid partitioning pathways and may act synergistically with GLP-1 receptor signalling in energy-balance models

Ent2 complex was crystallized with a 2:1 (protein:precipitant) ratio in a 0.2 M lithium sulphate, 0.1 M Bis-Tris pH 5.5, 25%(w/v) PEG 3350 solution at 19C