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Both have strong clinical evidence behind them and well-established safety profiles

Compared to flavones, flavonols have a hydroxyl group at the 3-position of the C-ring, which can be glycosylated

Most patients are between 40 and 60 years old when symptoms become severe enough to seek care

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Trends Plant Sci 5:193198 Eltelib HA, Fujikawa Y, Esaka M (2012) Overexpression of the acerola ( Malpighia glabra ) monodehydroascorbatereductase gene in transgenic tobacco plants results in increased ascorbate levels and enhanced tolerance to salt stress